Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human
IKKa/Ikkb around the phosphorylation site of Serine 180/181 (C-T-SP-F-V).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using
epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed
by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityIKKα/Ikkβ (phospho-Ser180/181) Antibody detects endogenous levels of IKKa/Ikkb only
when phosphorylated at Serine 180/181.
ReferencesBaeuerle, P.A. and Baltimore, D. (1988) Science 242, 540-6.
Chen, Z.J. et al. (1996) Cell 84, 853-62.
Delhase, M. et al. (1999) Science 284, 309-13.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells