Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human α-
Synuclein around the phosphorylation site of tyrosine 133 (E-G-YP-Q-D).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using
epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed
by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivityα-Synuclein (phospho-Tyr133) antibody detects endogenous levels ofα-Synuclein only
when phosphorylated at tyrosine 133.
ReferencesKozikowski AP, et al. (2006)ChemMedChem. 1(2):256-66.
Jakowec MW,et al.(2001)Dev Neurosci.23(2):91-9.
El-Agnaf OM,et al.(1998)FEBS Lett. 440(1-2):67-70.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells