Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Integrin β3 around the phosphorylation site of tyrosine 785 (I-T-YP-R-G).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityIntegrin β3 (Phospho-Tyr785) antibody detects endogenous levels of Integrin β3 only when phosphorylated at tyrosine 785.
ReferencesSujoy Bhattacharya, et al. (2006) Biochem J. August 1; 397(Pt 3): 437–447
Courter DL, et al. (2005) J Biol Chem Apr 01; 280(13): 12145-12151
Chandhoke SK, et al. (2004) J Cell Sci Mar 15; 117(Pt 8): 1431-1441
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells