Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human p56Dok-2 around the phosphorylation site of tyrosine 299 (G-E-YP-A-V).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivityp56Dok-2 (phospho-Tyr299) antibody detects endogenous levels of p56Dok-2 only when phosphorylated at tyrosine 299.
ReferencesFeng Cong, et,al. (1999) Mol. Cell. Biol ; 19: 8314 - 8325.
Serge Lemay, et,al. (2000) Mol. Cell. Biol ; 20: 2743 - 2754.
Ute Schaeper, et,al.(2000) J. Cell Biol ; 149: 1419.
Miyuki Honma, et,al. (2006) Genes Cells; 11: 143 - 151.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells