Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human p62Dok around the phosphorylation site of tyrosine 398 (E-G-YP-E-L).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivityp62Dok (phospho-Tyr398) antibody detects endogenous levels of p62Dok only when phosphorylated at tyrosine 398.
ReferencesMichael J. Wick, et al. (2001) J. Biol. Chem ; 276: 42843 - 42850.
Paul D. Simoncic, et al. (2006) Mol. Cell. Biol ; 26: 4149 - 4160.
Nadia Dubé, et al. (2004) PNAS ; 101: 1834.
Adam C. Yopp, et al. (2005) J. Immunol ; 175: 2913 - 2924.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells