Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human p62Dok around the phosphorylation site of tyrosine 362 (P-I-YP-D-E).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivityp62Dok (phospho-Tyr362) antibody detects endogenous levels of p62Dok only when phosphorylated at tyrosine 362.
ReferencesZhou Songyang, et al. (2001) J. Biol. Chem ; 276: 2459 - 2465.
Jean-Guy Némorin, et al. (2000) J. Biol. Chem ; 275: 14590.
Yuji Yamanashi, et al. (2000) Genes & Dev ; 14: 11.
Ibuki Kato, et al. (2002) J. Immunol ; 168: 629.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells