Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Tau around the phosphorylation site of serine 422 (V-D-SP-P-Q).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityTau (phospho- Ser422) antibody detects endogenous levels of Tau only when phosphorylated at serine 422.
ReferencesBuerger K,et al.(2007)Brain. 130(Pt 10):e82.
Grünblatt E,et al.(2007)J Neurochem. 101(3):757-70.
Skrabana R, (2006)Bratisl Lek Listy.107(9-10):354-8.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells