Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Merlin around the phosphorylation site of serine 518 (R-L-SP-M-E).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityMerlin (phospho-Ser518) antibody detects endogenous levels of Merlin only when phosphorylated at serine 518.
ReferencesGuang-Hui Xiao, et,al. (2005) Mol. Cell. Biol ; 25: 2384 - 2394.
Hi-Su Yang, et,al. (2006) Cancer Res ; 66: 2708 - 2715.
R Bohni, et,al. (1994) J. Biol. Chem ; 269: 14541 - 14545.
Adam J. Ratner, et,al. (2001) J. Biol. Chem ; 276: 19267 - 19275.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells