Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Met around the phosphorylation site of tyrosine 1349 (E-H-YP-V-H).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityMet (phospho-Tyr1349) antibody detects endogenous levels of Met only when phosphorylated at tyrosine 1349.
ReferencesFan S, et al. (2001) Mol Cell Biol; 21(15): 4968-4984
Schiering N, et al. (2003) Proc Natl Acad Sci U S A; 100(22): 12654-12659
Plopper GE, et al. (1995) Mol Biol Cell; 6(10): 1349-1365
Ponzetto C, et al. (1993) Mol Cell Biol; 13(8): 4600-4608
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells