Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Rb around the phosphorylation site of serine 795 (P-S-SP-P-L).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityRb (phospho-Ser795) antibody detects endogenous levels of Rb only when phosphorylated at serine 795.
ReferencesRubin SM, et al. (2005) Cell.123 (6): 1093-1106.
Wallick CJ, et al. (2005) Oncogene.24 (36): 5606-5618.
Leibundgut K, et al. (2005) Stem Cells. 23(7):1002-1011.
Roesch A, et al. (2005) Mod Pathol.18 (4): 565-572.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells