Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Tau around the phosphorylation site of threonine 181 (P-K-TP-P-P).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityTau (phospho-Thr181) antibody detects endogenous levels of Tau only when phosphorylated at threonine 181.
ReferencesPuig B, et al.(2005) Acta Neuropathol (Berl). 110(3):261-268.
Pérez M, et al.(2005) Neuroscience. 130(2): 339-347.
Fellgiebel A, et al.(2004) Biol Psychiatry. 56(4): 279-283.
del C Alonso A, et al.(2004) J Biol Chem. 279(33): 34873-34881.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells