Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Tau around the phosphorylation site of serine 356 (I-G-SP-L-D).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityTau (phospho-Ser356) antibody detects endogenous levels of Tau only when phosphorylated at serine356.
ReferencesPuig B, et al. (2005) Acta Neuropathol (Berl). 110(3):261-268.
DeGiorgis JA, et al. (2005) J Proteome Res. 4(2): 306-315.
Alonso Adel C, et al. (2004) J Biol Chem. 279(33): 34873-34881.
Kyriakis J M, et al. (1994) Nature. 369: 156-160.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells