Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Src around the phosphorylation site of tyrosine 418 (N-E-YP-T-A).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivitySrc (phospho-Tyr418) antibody detects endogenous levels of Src only when phosphorylated at tyrosine 418.
ReferencesDufilho M, et al. (2005) J Biol Chem. 280(43):35999-36006.
Sanders MA, et al. (2005) J Biol Chem. 280(25): 23516-23522.
Murugappan S, et al. (2005) Blood. 106(2):550-557.
Gu JJ, et al. (2005) Blood. 105(8): 3270-3277.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells