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H-89PKA Inhibitor
Datasheet   

  • Catalog Number:

    E1B1643

  • Amount:

  • PHYSICAL APPEARANCE: Off-white solid (m.p. 141-143°C)
    MOLECULAR FORMULA: C20H20BrN3O2S·2HCl

  • Molecular Weight:

    519.2

  • Purity:

    99% (TLC: 10% Methanol/methylene chloride; Rf = 0.65)

  • Storage/Stability:

    Store solutions at -20°C for up to 1 year.

  • Recommended Dilutions:

    Potent, selective and widely used inhibitor of PKA (Ki = 48 nM). Cell permeable. Concentration range for cultured cells 30-100 μM: osteoblastic cells, renal proximal tubule cells and Xenopus oocytes.

  • References:

    1​ T.Chijiwa et al. J.Biol.Chem. 1990 265 5267
    2​ M.Muroi and T.Suzuki Cell Signal 1993 5 289
    3​ M.Fujihara et al. J.Biol.Chem. 1993 268 14898
    4​ A.Azarani et al. J.Biol.Chem. 1995 270 23166
    5​ A.Azarani et al. J.Biol.Chem. 1995 270 20004
    6​ A.Azarani et al. J.Biol.Chem. 1995 270 17898
    The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.

  • Price:

    40$

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