DUOX1 Polyclonal Antibody
Datasheet
Catalog Number:
E98583Amount:
100ulPrice:
225$Swiss-Prot No.:
Q9NRD9Storage/Stability:
Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.Immunogen:
Recombinant protein of human DUOX1 (NP_059130.2).Purification:
Affinity purificationReactivity:
Mouse,RatOther Names:
_Background:
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.Gene ID:
53905Source:
RabbitAntibody type:
Polyclonal AntibodiesIsotype:
IgGMolecular Weight:
137kDa/177kDaRecommended Dilutions:
WB 1:500 - 1:2000
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Catalog Number
- Amount:100ul
- Price:225$
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