Catalog Number:
E97481Amount:
100ulAntibody type:
Polyclonal AntibodyApplications:
WB IHC IFReactivity:
Human Mouse RatMolecular Weight:
60kDaPrice:
255$Immunogen:
Recombinant protein of human ASPSCR1Gene ID:
79058Swiss-Prot No.:
Q9BZE9Altername:
ASPCR1;ASPL;ASPS;RCC17;TUG;UBXD9;UBXN9Source:
RabbitIsotype:
IgGPurification:
Affinity purificationStorage/Stability:
Store at -20°C. Avoid freeze / thaw cycles.Background:
The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.Dilution:
WB 1:500 - 1:2000Shipping&Stablity:
Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.