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TMEM173
Datasheet   

  • Catalog Number:

    E93575

  • Amount:

    100ul

  • Price:

    255$

  • Research Area:

    Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells

  • Antibody type:

    Polyclonal Antibody

  • Applications:

    WB IHC

  • Reactivity:

    Human Mouse

  • Molecular Weight:

    42kDa

  • Immunogen:

    Recombinant protein of human TMEM173

  • Gene ID:

    340061

  • Swiss-Prot No.:

    Q86WV6

  • Altername:

    ERIS;MITA;MPYS;NET23;SAVI;STING;hMITA;hSTING

  • Source:

    Rabbit

  • Isotype:

    IgG

  • Purification:

    Affinity purification

  • Storage/Stability:

    Store at -20°C. Avoid freeze / thaw cycles.
    Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

  • Background:

    This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

  • Dilution:

    WB 1:500 - 1:2000
    IHC 1:50 - 1:100

  • Shipping&Stablity:

    Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

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  • Amount:100ul
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