POMCPolyclonal Antibody | EnoGene Biotech Co. Ltd

POMCPolyclonal Antibody
Datasheet

Catalog Number:
E93038
Amount:
100ul
Background:
This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation.
Species:
Rabbit
Isotype:
IgG
Storage/Stability:
Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Altername:
LPH; MSH; NPP; POC; ACTH; CLIP
Immunogen:
A synthetic peptide of human POMC
Purification:
Affinity purification
Reactivity:
H M R
Applications:
WB
Molecular Weight:
29kDa
Swiss-Prot No.:
P01189
Gene ID:
5443
WB 1:500 - 1:2000
Western blot analysis of extracts of HepG2cell line, using POMCantibody..

POMCPolyclonal Antibody
Datasheet