GRM8Polyclonal Antibody
Datasheet
Catalog Number:
E92964Amount:
100ulBackground:
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.Species:
RabbitIsotype:
IgGStorage/Stability:
Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.Altername:
GLUR8; mGlu8; GPRC1H; MGLUR8Immunogen:
A synthetic peptide of human GRM8Purification:
Affinity purificationReactivity:
H M RApplications:
WB IHCMolecular Weight:
102kDaSwiss-Prot No.:
O00222Gene ID:
2918
WB 1:500 - 1:2000
IHC 1:50- 1:200
- Western blot analysis of extracts of mouse braintissue, using GRM8antibody.
- Immunohistochemistryof paraffin-embeddedhuman ovarian cancer usingGRM8antibody.
Related Products
- BRCA1 (Phospho-Ser1524) Antibody Datasheet
Catalog Number:
E011117-1Amount:
50μg/50μlReactivity:
HumanApplications:
IHC: 1:50~1:100Swiss-Prot No.:
P38398Price:
145$
- BRCA1 (Phospho-Ser1524) Antibody Datasheet
Catalog Number:
E011117-2Amount:
100μg/100μlReactivity:
HumanApplications:
IHC: 1:50~1:100Swiss-Prot No.:
P38398Price:
225$
- JAK1(Phospho-Tyr1022) Antibody Datasheet
Catalog Number:
E011149-1Amount:
50μg/50μlReactivity:
Human, Mouse, RatApplications:
WB: 1:500~1:1000 IHC: 1:50~1:100Swiss-Prot No.:
P23458Price:
145$
- JAK1(Phospho-Tyr1022) Antibody Datasheet
Catalog Number:
E011149-2Amount:
100μg/100μlReactivity:
Human, Mouse, RatApplications:
WB: 1:500~1:1000 IHC: 1:50~1:100Swiss-Prot No.:
P23458Price:
225$
- BRCA1 (Phospho-Ser988) Antibody Datasheet
Catalog Number:
E011237-1Amount:
50μg/50μlReactivity:
HumanApplications:
IF:1:100~1:200Swiss-Prot No.:
P38398Price:
145$
Catalog Number
- Amount:100ul
- Price:255$
Contact us
Categories by research area
Categories by product type
- Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits