NUAK2Polyclonal Antibody
Datasheet
Catalog Number:
E91079Amount:
100ulBackground:
SNARK was identified as an SNF1/AMPK-related kinase and member of the AMPK catalytic subunit family (1,2). This enzyme was separately identified as a TNFα-induced SNF1-like kinase 2 (NUAK2) (3). The kinase activity of SNARK/NUAK2 is increased by AMP and AICAR (1). SNARK/NUAK2 activity is regulated by a variety of cellular stresses such as endoplasmic reticulum (ER) stress and oxidative stresses (4), suggesting that SNARK/NUAK2 is a signaling molecule involved in the cell stress response (4).Species:
RabbitIsotype:
IgGStorage/Stability:
Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.Altername:
NUAK2;DKFZp434J037;DKFZp686F01113;FLJ90349;SNARK ;Immunogen:
Recombinant proteinof human NUAK2Purification:
Affinity purificationReactivity:
H M RApplications:
WB IHCMolecular Weight:
70kDaSwiss-Prot No.:
Q9H093Gene ID:
81788References:
1. Lefebvre, D.L. et al. (2001) Biochem J 355, 297-305. 2. Suzuki, A. et al. (2003) Biochem Biophys Res Commun 311, 156-61. 3. Yamamoto, H. et al. (2008) Biochem Biophys Res Commun 365, 541-7. 4. Lefebvre, D.L. and Rosen, C.F. (2005) Biochim Biophys Acta 1724, 71-85.
WB 1:500 - 1:2000
IHC 1:50- 1:200
- Western blot analysis of extracts of various celllines, using NUAK2 antibody.
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