Catalog Number:
E910461Amount:
100ulAntibody type:
Polyclonal AntibodyApplications:
WBReactivity:
Human Mouse RatMolecular Weight:
57kDaPrice:
255$Immunogen:
Recombinant protein of human PHGDHGene ID:
26227Swiss-Prot No.:
O43175Altername:
3-PGDH;3PGDH;HEL-S-113;NLS;NLS1;PDG;PGAD;PGD;PGDH;PHGDHD;SERASource:
RabbitIsotype:
IgGPurification:
Affinity purificationStorage/Stability:
Store at -20°C. Avoid freeze / thaw cycles.Background:
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.Dilution:
WB 1:500 - 1:2000Shipping&Stablity:
Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.