ATG13Polyclonal Antibody
Datasheet
Catalog Number:
E90690Amount:
100ulBackground:
The autophagy-related protein 13 (Atg13) plays an important role in the formation of autophagosomes. Autophagosomes are formed in response to nutrient deprivation and function as the transport vesicles for organelles, proteins, and protein complexes targeted for lysosomes that digest these cargos to produce energy and nutrients. Atg13 is activated by the mTOR pathway and forms a complex with the FIP200 protein. This complex is involved in enhancing the activity of the ULK1 kinase which is required for the formation of autophagosomes. Atg13/FIP200 faciliates the localization of ULK1 to pre-autophagosomes, and subsequently stabilizes ULK1. Autophagy is an important process in development, growth, and cell differentiation, and disruption of this process may contribute to cancer, aging, and neurodegenerative diseases.Species:
RabbitIsotype:
IgGStorage/Stability:
Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.Altername:
KIAA0652;ATG13;FLJ20698 ;Immunogen:
Recombinant proteinof human ATG13Purification:
Affinity purificationReactivity:
H M RApplications:
WB IHCMolecular Weight:
57kDaSwiss-Prot No.:
O75143Gene ID:
9776
WB 1:500 - 1:2000
IHC 1:50- 1:200
- Western blot analysis of extracts of variouscell lines, using ATG13 antibody.
Related Products
- BRCA1 (Phospho-Ser1524) Antibody Datasheet
Catalog Number:
E011117-1Amount:
50μg/50μlReactivity:
HumanApplications:
IHC: 1:50~1:100Swiss-Prot No.:
P38398Price:
145$
- BRCA1 (Phospho-Ser1524) Antibody Datasheet
Catalog Number:
E011117-2Amount:
100μg/100μlReactivity:
HumanApplications:
IHC: 1:50~1:100Swiss-Prot No.:
P38398Price:
225$
- JAK1(Phospho-Tyr1022) Antibody Datasheet
Catalog Number:
E011149-1Amount:
50μg/50μlReactivity:
Human, Mouse, RatApplications:
WB: 1:500~1:1000 IHC: 1:50~1:100Swiss-Prot No.:
P23458Price:
145$
- JAK1(Phospho-Tyr1022) Antibody Datasheet
Catalog Number:
E011149-2Amount:
100μg/100μlReactivity:
Human, Mouse, RatApplications:
WB: 1:500~1:1000 IHC: 1:50~1:100Swiss-Prot No.:
P23458Price:
225$
- BRCA1 (Phospho-Ser988) Antibody Datasheet
Catalog Number:
E011237-1Amount:
50μg/50μlReactivity:
HumanApplications:
IF:1:100~1:200Swiss-Prot No.:
P38398Price:
145$
Catalog Number
- Amount:100ul
- Price:255$
Contact us
Categories by research area
Categories by product type
- Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits