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GRIA2 Polyclonal Antibody

Human,Mouse,Rat
P42262
Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Price225$
Storage/StabilityStore at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
ImmunogenRecombinant protein of human GRIA2 (NP_001077088.1).
PurificationAffinity purification
Other Names_
BackgroundGlutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.
Gene ID2891
Antibody typePolyclonal Antibodies

Product Information

IsotypeIgG
Molecular Weight93kDa/98kDa/100kDa
Recommended DilutionsWB 1:500 - 1:2000
IF 1:50 - 1:200

Conjugated Antibody

This product is also available conjugated. Format: E90111a-Conjugate. Price: $485 / Size: 100μl.

E90111a-FITC$485 / 100μlE90111a-Biotin$485 / 100μlE90111a-HRP$485 / 100μlE90111a-AP$485 / 100μlE90111a-AF350$485 / 100μlE90111a-AF405M$485 / 100μlE90111a-AF488$485 / 100μlE90111a-AF514$485 / 100μlE90111a-AF532$485 / 100μlE90111a-AF555$485 / 100μlE90111a-AF568$485 / 100μlE90111a-AF405S$485 / 100μlE90111a-AF405L$485 / 100μlE90111a-AF546$485 / 100μlE90111a-AF594$485 / 100μlE90111a-AF610$485 / 100μlE90111a-AF635$485 / 100μlE90111a-AF647$485 / 100μlE90111a-AF680$485 / 100μlE90111a-AF700$485 / 100μlE90111a-AF750$485 / 100μlE90111a-AF790$485 / 100μlE90111a-APC$485 / 100μlE90111a-PE$485 / 100μlE90111a-Cy3$485 / 100μlE90111a-Cy5$485 / 100μlE90111a-Cy5.5$485 / 100μlE90111a-Cy7$485 / 100μlE90111a-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.