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SARS Antibody (N-term)
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  • Catalog Number:

    E45R30726G-4

  • Amount:

    50 µl

  • Cite ID#:

    EN5476821

  • Price:

    295$

  • Type:

    Rabbit Polyclonal Antibody

  • Host:

    Rabbit

  • Reactivity:

    H

  • Immunogen:

    This SARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-169 amino acids from the N-terminal region of human SARS.

  • Purification:

    Affinity chromatography purified.

  • Gene Name:

    SARS1 (HGNC:10537)

  • Gene ID:

    6301

  • Swiss-Prot No.:

    P49591

  • Function:

    Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser) (PubMed:22353712, PubMed:24095058, PubMed:9431993, PubMed:26433229, PubMed:28236339). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (PubMed:9431993, PubMed:26433229, PubMed:28236339). In the nucleus, binds to the VEGFA core promoter and prevents MYC binding and transcriptional activation by MYC (PubMed:24940000). Recruits SIRT2 to the VEGFA promoter, promoting deacetylation of histone H4 at 'Lys-16' (H4K16). Thereby, inhibits the production of VEGFA and sprouting angiogenesis mediated by VEGFA (PubMed:19423848, PubMed:19423847, PubMed:24940000).

  • Summary:

    Tissue Location:
    Brain..

  • Form:

    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

  • Storage/Stability:

    Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

  • Applications:

    WB, IHC-P

  • Dilution:

    WB--1:1000
    IHC-P--1:100~500

  • Altername:

    Serine--tRNA ligase, cytoplasmic, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase, SARS, SERS

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SARS Antibody (N-term) | EnoGene Biotech Co. Ltd