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Phospho-PDK1/PDPK1-S241 Rabbit pAb
$510/ 100 µl
QuantityTotal: $510
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5518427
TypePhosphorylated Antibodies
HostRabbit
Positive control293
IsotypeIgG
SummarySerine/threonine kinase which acts as a master kinase, phosphorylating and activating a subgroup of the AGC family of protein kinases. Plays a central role in the transduction of signals from insulin by providing the activating phosphorylation to PKB/AKT1, thus propagating the signal to downstream targets controlling cell proliferation and survival, as well as glucose and amino acid uptake and storage. Negatively regulates the TGF-beta-induced signaling . Activates PPARG transcriptional activity and promotes adipocyte differentiation. Activates the NF-kappa-B pathway via phosphorylation of IKKB. The tyrosine phosphorylated form is crucial for the regulation of focal adhesions by angiotensin II. Controls proliferation, survival, and growth of developing pancreatic cells. Participates in the regulation of Ca(2+) entry and Ca(2+)-activated K(+) channels of mast cells. Essential for the motility of vascular endothelial cells (ECs) and is involved in the regulation of their chemotaxis. Plays a critical role in cardiac homeostasis by serving as a dual effector for cell survival and beta-adrenergic response. Plays an important role during thymocyte development by regulating the expression of key nutrient receptors on the surface of pre-T cells and mediating Notch-induced cell growth and proliferative responses. Provides negative feedback inhibition to toll-like receptor-mediated NF-kappa-B activation in macrophages. Isoform 3 is catalytically inactive.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price510$
ImmunogenA phospho specific peptide corresponding to residues surrounding S241 of human PDK1/PDPK1
PurificationAffinity purification
Gene ID5170
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:100 - 1:200
IHC 1:50 - 1:100
IF 1:100 - 1:200
All Names
AlternamePDPK1; PDK1; PDPK2; PDPK2P; PRO0461
Conjugated Antibody
This product is also available conjugated. Format: E45R30392N-Conjugate. Price: $485 / Size: 100μl.
E45R30392N-FITC$485 / 100μlE45R30392N-Biotin$485 / 100μlE45R30392N-HRP$485 / 100μlE45R30392N-AP$485 / 100μlE45R30392N-AF350$485 / 100μlE45R30392N-AF405M$485 / 100μlE45R30392N-AF488$485 / 100μlE45R30392N-AF514$485 / 100μlE45R30392N-AF532$485 / 100μlE45R30392N-AF555$485 / 100μlE45R30392N-AF568$485 / 100μlE45R30392N-AF405S$485 / 100μlE45R30392N-AF405L$485 / 100μlE45R30392N-AF546$485 / 100μlE45R30392N-AF594$485 / 100μlE45R30392N-AF610$485 / 100μlE45R30392N-AF635$485 / 100μlE45R30392N-AF647$485 / 100μlE45R30392N-AF680$485 / 100μlE45R30392N-AF700$485 / 100μlE45R30392N-AF750$485 / 100μlE45R30392N-AF790$485 / 100μlE45R30392N-APC$485 / 100μlE45R30392N-PE$485 / 100μlE45R30392N-Cy3$485 / 100μlE45R30392N-Cy5$485 / 100μlE45R30392N-Cy5.5$485 / 100μlE45R30392N-Cy7$485 / 100μlE45R30392N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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