Product Information
Cite ID#EN5518408
TypePolyclonal Antibodies
HostRabbit
Positive controlBxPC-3, Rat heart
IsotypeIgG
SummaryThis gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 18-212 of human Endothelin 1 (NP_001946.3).
PurificationAffinity purification
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:100
All Names
AlternameEDN1; ARCND3; ET1; HDLCQ7; PPET1; QME; endothelin-1