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DNA topoisomerase II alpha (TOP2A) Rabbit pAb

Human
WB (H460, A549, Homo sapiens)
IF (Homo sapiens)
P11388
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5518393
TypePolyclonal Antibodies
HostRabbit
Positive controlHepG2
IsotypeIgG
SummaryThis gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, pH7.3.
Price409$
ImmunogenA synthetic peptide of human DNA topoisomerase II alpha (DNA topoisomerase II alpha (TOP2A))
PurificationAffinity purification
Gene ID7153
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:20 - 1:50

All Names

AlternameTOP2A; TOP2; TP2A

Conjugated Antibody

This product is also available conjugated. Format: E45R30358N-Conjugate. Price: $485 / Size: 100μl.

E45R30358N-FITC$485 / 100μlE45R30358N-Biotin$485 / 100μlE45R30358N-HRP$485 / 100μlE45R30358N-AP$485 / 100μlE45R30358N-AF350$485 / 100μlE45R30358N-AF405M$485 / 100μlE45R30358N-AF488$485 / 100μlE45R30358N-AF514$485 / 100μlE45R30358N-AF532$485 / 100μlE45R30358N-AF555$485 / 100μlE45R30358N-AF568$485 / 100μlE45R30358N-AF405S$485 / 100μlE45R30358N-AF405L$485 / 100μlE45R30358N-AF546$485 / 100μlE45R30358N-AF594$485 / 100μlE45R30358N-AF610$485 / 100μlE45R30358N-AF635$485 / 100μlE45R30358N-AF647$485 / 100μlE45R30358N-AF680$485 / 100μlE45R30358N-AF700$485 / 100μlE45R30358N-AF750$485 / 100μlE45R30358N-AF790$485 / 100μlE45R30358N-APC$485 / 100μlE45R30358N-PE$485 / 100μlE45R30358N-Cy3$485 / 100μlE45R30358N-Cy5$485 / 100μlE45R30358N-Cy5.5$485 / 100μlE45R30358N-Cy7$485 / 100μlE45R30358N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

DNA topoisomerase II alpha (TOP2A) Rabbit pAb | EnoGene Biotech Co. Ltd