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[KO Validated] Laminin beta 1 Rabbit pAb
$477/ 100 µl
QuantityTotal: $477
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5518338
TypePolyclonal Antibodies
HostRabbit
Positive controlHeLa
IsotypeIgG
SummaryLaminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. This gene encodes the beta chain isoform laminin, beta 1. The beta 1 chain has 7 structurally distinct domains which it shares with other beta chain isomers. The C-terminal helical region containing domains I and II are separated by domain alpha, domains III and V contain several EGF-like repeats, and domains IV and VI have a globular conformation. Laminin, beta 1 is expressed in most tissues that produce basement membranes, and is one of the 3 chains constituting laminin 1, the first laminin isolated from Engelbreth-Holm-Swarm (EHS) tumor. A sequence in the beta 1 chain that is involved in cell attachment, chemotaxis, and binding to the laminin receptor was identified and shown to have the capacity to inhibit metastasis.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price477$
ImmunogenRecombinant protein of human Laminin beta 1.
PurificationAffinity purification
Gene ID3912
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:1000 - 1:4000
IHC 1:10 - 1:200
IF 1:50 - 1:200
IHC 1:10 - 1:200
IF 1:50 - 1:200
All Names
AlternameLAMB1; CLM; LIS5
Conjugated Antibody
This product is also available conjugated. Format: E45R30303N-Conjugate. Price: $485 / Size: 100μl.
E45R30303N-FITC$485 / 100μlE45R30303N-Biotin$485 / 100μlE45R30303N-HRP$485 / 100μlE45R30303N-AP$485 / 100μlE45R30303N-AF350$485 / 100μlE45R30303N-AF405M$485 / 100μlE45R30303N-AF488$485 / 100μlE45R30303N-AF514$485 / 100μlE45R30303N-AF532$485 / 100μlE45R30303N-AF555$485 / 100μlE45R30303N-AF568$485 / 100μlE45R30303N-AF405S$485 / 100μlE45R30303N-AF405L$485 / 100μlE45R30303N-AF546$485 / 100μlE45R30303N-AF594$485 / 100μlE45R30303N-AF610$485 / 100μlE45R30303N-AF635$485 / 100μlE45R30303N-AF647$485 / 100μlE45R30303N-AF680$485 / 100μlE45R30303N-AF700$485 / 100μlE45R30303N-AF750$485 / 100μlE45R30303N-AF790$485 / 100μlE45R30303N-APC$485 / 100μlE45R30303N-PE$485 / 100μlE45R30303N-Cy3$485 / 100μlE45R30303N-Cy5$485 / 100μlE45R30303N-Cy5.5$485 / 100μlE45R30303N-Cy7$485 / 100μlE45R30303N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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