Product Information
Cite ID#EN5518265
TypePhosphorylated Antibodies
HostRabbit
IsotypeIgG
SummaryHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
ImmunogenA phospho specific peptide corresponding to residues surrounding S39 of human HDAC8
PurificationAffinity purification
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionIHC 1:50 - 1:100
IF 1:100 - 1:200
All Names
AlternameHDAC8; CDA07; CDLS5; HD8; HDACL1; MRXS6; RPD3; WTS