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Human IgM Rabbit pAb
Human
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5518173
TypePolyclonal Antibodies
HostRabbit
Positive controlRaji
IsotypeIgG
SummaryImmunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule is made up of 2 identical heavy chains and 2 identical light chains joined by disulfide bonds so that each heavy chain is linked to a light chain and the 2 heavy chains are linked together. Each Ig heavy chain has an N-terminal variable (V) region containing the antigen-binding site and a C-terminal constant (C) region, encoded by an individual C region gene, that determines the isotype of the antibody and provides effector or signaling functions. The heavy chain V region is encoded by 1 each of 3 types of genes: V genes, joining (J) genes, and diversity (D) genes. The C region genes are clustered downstream of the V region genes within the heavy chain locus on chromosome 14. The IGHM gene encodes the C region of the mu heavy chain, which defines the IgM isotype. Naive B cells express the transmembrane forms of IgM and IgD on their surface. During an antibody response, activated B cells can switch to the expression of individual downstream heavy chain C region genes by a process of somatic recombination known as isotype switching. In addition, secreted Ig forms that act as antibodies can be produced by alternative RNA processing of the heavy chain C region sequences. Although the membrane forms of all Ig isotypes are monomeric, secreted IgM forms pentamers, and occasionally hexamers, in plasma.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenA synthetic Peptide of human IGHM
PurificationAffinity purification
Gene ID3507
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:200 - 1:1000
All Names
AlternameIGHM; AGM1; MU; VH
Conjugated Antibody
This product is also available conjugated. Format: E45R30138N-Conjugate. Price: $485 / Size: 100μl.
E45R30138N-FITC$485 / 100μlE45R30138N-Biotin$485 / 100μlE45R30138N-HRP$485 / 100μlE45R30138N-AP$485 / 100μlE45R30138N-AF350$485 / 100μlE45R30138N-AF405M$485 / 100μlE45R30138N-AF488$485 / 100μlE45R30138N-AF514$485 / 100μlE45R30138N-AF532$485 / 100μlE45R30138N-AF555$485 / 100μlE45R30138N-AF568$485 / 100μlE45R30138N-AF405S$485 / 100μlE45R30138N-AF405L$485 / 100μlE45R30138N-AF546$485 / 100μlE45R30138N-AF594$485 / 100μlE45R30138N-AF610$485 / 100μlE45R30138N-AF635$485 / 100μlE45R30138N-AF647$485 / 100μlE45R30138N-AF680$485 / 100μlE45R30138N-AF700$485 / 100μlE45R30138N-AF750$485 / 100μlE45R30138N-AF790$485 / 100μlE45R30138N-APC$485 / 100μlE45R30138N-PE$485 / 100μlE45R30138N-Cy3$485 / 100μlE45R30138N-Cy5$485 / 100μlE45R30138N-Cy5.5$485 / 100μlE45R30138N-Cy7$485 / 100μlE45R30138N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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