World supplier of antibodies, antigens and kits since 2007

Welcome, Sign in or Register

My Cart(0)
Other Products

IREB1 Rabbit pAb

E45R30067NDatasheetCOAMSDS
Mouse, Rat
P21399
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5518102
TypePolyclonal Antibodies
HostRabbit
Positive controlMouse liver, Mouse kidney, Mouse ovary, Rat kidney
IsotypeIgG
SummaryThe protein encoded by this gene is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to iron-responsive elements (IREs), which are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. When the protein binds to IRE, it results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degraded transferrin receptor mRNA. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alternative splicing results in multiple transcript variants
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenA synthetic peptide of human IREB1
PurificationAffinity purification
Gene ID48
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:1000
IHC 1:50 - 1:100

All Names

AlternameACO1; ACONS; HEL60; IREB1; IREBP; IREBP1; IRP1
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R30067N-Conjugate. Price: $485 / Size: 100μl.

E45R30067N-FITC$485 / 100μlE45R30067N-Biotin$485 / 100μlE45R30067N-HRP$485 / 100μlE45R30067N-AP$485 / 100μlE45R30067N-AF350$485 / 100μlE45R30067N-AF405M$485 / 100μlE45R30067N-AF488$485 / 100μlE45R30067N-AF514$485 / 100μlE45R30067N-AF532$485 / 100μlE45R30067N-AF555$485 / 100μlE45R30067N-AF568$485 / 100μlE45R30067N-AF405S$485 / 100μlE45R30067N-AF405L$485 / 100μlE45R30067N-AF546$485 / 100μlE45R30067N-AF594$485 / 100μlE45R30067N-AF610$485 / 100μlE45R30067N-AF635$485 / 100μlE45R30067N-AF647$485 / 100μlE45R30067N-AF680$485 / 100μlE45R30067N-AF700$485 / 100μlE45R30067N-AF750$485 / 100μlE45R30067N-AF790$485 / 100μlE45R30067N-APC$485 / 100μlE45R30067N-PE$485 / 100μlE45R30067N-Cy3$485 / 100μlE45R30067N-Cy5$485 / 100μlE45R30067N-Cy5.5$485 / 100μlE45R30067N-Cy7$485 / 100μlE45R30067N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

Related Products

RASH/RASK/RASN AntibodyRASH/RASK/RASN AntibodyE11-0313,$225SHIP AntibodySHIP AntibodyE11-0320,$225Syk AntibodySyk AntibodyE11-0332,$225CTRO AntibodyCTRO AntibodyE11-10038,$225TUSC2 AntibodyTUSC2 AntibodyE11-10196,$225
IREB1 Rabbit pAb | EnoGene Biotech Co. Ltd