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GNAS Rabbit pAb
Human, Mouse
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5518011
TypePolyclonal Antibodies
HostRabbit
Positive controlNCI-H460, SW620, Mouse skeletal muscle, Mouse brain, Mouse heart
IsotypeIgG
SummaryThis locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant protein of human GNAS
PurificationAffinity purification
Gene ID2778
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
All Names
AlternameGNAS; AHO; C20orf45; GNAS1; GPSA; GSA; GSP; NESP; POH; SCG6; SgVI
Conjugated Antibody
This product is also available conjugated. Format: E45R29976N-Conjugate. Price: $485 / Size: 100μl.
E45R29976N-FITC$485 / 100μlE45R29976N-Biotin$485 / 100μlE45R29976N-HRP$485 / 100μlE45R29976N-AP$485 / 100μlE45R29976N-AF350$485 / 100μlE45R29976N-AF405M$485 / 100μlE45R29976N-AF488$485 / 100μlE45R29976N-AF514$485 / 100μlE45R29976N-AF532$485 / 100μlE45R29976N-AF555$485 / 100μlE45R29976N-AF568$485 / 100μlE45R29976N-AF405S$485 / 100μlE45R29976N-AF405L$485 / 100μlE45R29976N-AF546$485 / 100μlE45R29976N-AF594$485 / 100μlE45R29976N-AF610$485 / 100μlE45R29976N-AF635$485 / 100μlE45R29976N-AF647$485 / 100μlE45R29976N-AF680$485 / 100μlE45R29976N-AF700$485 / 100μlE45R29976N-AF750$485 / 100μlE45R29976N-AF790$485 / 100μlE45R29976N-APC$485 / 100μlE45R29976N-PE$485 / 100μlE45R29976N-Cy3$485 / 100μlE45R29976N-Cy5$485 / 100μlE45R29976N-Cy5.5$485 / 100μlE45R29976N-Cy7$485 / 100μlE45R29976N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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