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Phospho-MAP3K5-T845 Rabbit pAb

Human
O35099
$510/ 100 µl
Quantity
Total: $510

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5517973
TypePhosphorylated Antibodies
HostRabbit
Positive control293T
IsotypeIgG
SummarySerine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signaling for determination of cell fate such as differentiation and survival. Plays a crucial role in the apoptosis signal transduction pathway through mitochondria-dependent caspase activation. MAP3K5/ASK1 is required for the innate immune response, which is essential for host defense against a wide range of pathogens. Mediates signal transduction of various stressors like oxidative stress as well as by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF or lipopolysaccharide (LPS. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K4/SEK1, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7. These MAP2Ks in turn activate p38 MAPKs and c-jun N-terminal kinases (JNKs. Both p38 MAPK and JNKs control the transcription factors activator protein-1 (AP-1.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price510$
ImmunogenA phospho specific peptide corresponding to residues surrounding T845 of human MAP3K5.
PurificationAffinity purification
Gene ID26408
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000

All Names

AlternameA; AS; ASK; ASK1; Mekk5; MAPKKK5; 7420452D20Rik

Conjugated Antibody

This product is also available conjugated. Format: E45R29938N-Conjugate. Price: $485 / Size: 100μl.

E45R29938N-FITC$485 / 100μlE45R29938N-Biotin$485 / 100μlE45R29938N-HRP$485 / 100μlE45R29938N-AP$485 / 100μlE45R29938N-AF350$485 / 100μlE45R29938N-AF405M$485 / 100μlE45R29938N-AF488$485 / 100μlE45R29938N-AF514$485 / 100μlE45R29938N-AF532$485 / 100μlE45R29938N-AF555$485 / 100μlE45R29938N-AF568$485 / 100μlE45R29938N-AF405S$485 / 100μlE45R29938N-AF405L$485 / 100μlE45R29938N-AF546$485 / 100μlE45R29938N-AF594$485 / 100μlE45R29938N-AF610$485 / 100μlE45R29938N-AF635$485 / 100μlE45R29938N-AF647$485 / 100μlE45R29938N-AF680$485 / 100μlE45R29938N-AF700$485 / 100μlE45R29938N-AF750$485 / 100μlE45R29938N-AF790$485 / 100μlE45R29938N-APC$485 / 100μlE45R29938N-PE$485 / 100μlE45R29938N-Cy3$485 / 100μlE45R29938N-Cy5$485 / 100μlE45R29938N-Cy5.5$485 / 100μlE45R29938N-Cy7$485 / 100μlE45R29938N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

Phospho-MAP3K5-T845 Rabbit pAb | EnoGene Biotech Co. Ltd