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HMGCR Rabbit pAb

Human, Mouse, Rat
P04035
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5517937
TypePolyclonal Antibodies
HostRabbit
Positive controlHeLa, Mouse spleen, Rat brain
IsotypeIgG
SummaryHMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 629-888 of human HMGCR (NP_000850.1).
PurificationAffinity purification
Gene ID3156
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IF 1:50 - 1:200

All Names

AlternameHMGCR; LDLCQ3; HMGCR

Conjugated Antibody

This product is also available conjugated. Format: E45R29902N-Conjugate. Price: $485 / Size: 100μl.

E45R29902N-FITC$485 / 100μlE45R29902N-Biotin$485 / 100μlE45R29902N-HRP$485 / 100μlE45R29902N-AP$485 / 100μlE45R29902N-AF350$485 / 100μlE45R29902N-AF405M$485 / 100μlE45R29902N-AF488$485 / 100μlE45R29902N-AF514$485 / 100μlE45R29902N-AF532$485 / 100μlE45R29902N-AF555$485 / 100μlE45R29902N-AF568$485 / 100μlE45R29902N-AF405S$485 / 100μlE45R29902N-AF405L$485 / 100μlE45R29902N-AF546$485 / 100μlE45R29902N-AF594$485 / 100μlE45R29902N-AF610$485 / 100μlE45R29902N-AF635$485 / 100μlE45R29902N-AF647$485 / 100μlE45R29902N-AF680$485 / 100μlE45R29902N-AF700$485 / 100μlE45R29902N-AF750$485 / 100μlE45R29902N-AF790$485 / 100μlE45R29902N-APC$485 / 100μlE45R29902N-PE$485 / 100μlE45R29902N-Cy3$485 / 100μlE45R29902N-Cy5$485 / 100μlE45R29902N-Cy5.5$485 / 100μlE45R29902N-Cy7$485 / 100μlE45R29902N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

HMGCR Rabbit pAb | EnoGene Biotech Co. Ltd