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PTEN Rabbit pAb

E45R29823NDatasheetCOAMSDS
Human, Rat
P60484
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5517858
TypePolyclonal Antibodies
HostRabbit
IsotypeIgG
SummaryThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. The use of a non-canonical (CUG) upstream initiation site produces a longer isoform that initiates translation with a leucine, and is thought to be preferentially associated with the mitochondrial inner membrane. This longer isoform may help regulate energy metabolism in the mitochondria. A pseudogene of this gene is found on chromosome 9. Alternative splicing and the use of multiple translation start codons results in multiple transcript variants encoding different isoforms.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant protein of human PTEN.
PurificationAffinity purification
Gene ID5728
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000

All Names

Altername10q23del; BZS; CWS1; DEC; GLM2; MHAM; MMAC1; PTEN1; TEP1; PTEN; PTENbeta
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R29823N-Conjugate. Price: $485 / Size: 100μl.

E45R29823N-FITC$485 / 100μlE45R29823N-Biotin$485 / 100μlE45R29823N-HRP$485 / 100μlE45R29823N-AP$485 / 100μlE45R29823N-AF350$485 / 100μlE45R29823N-AF405M$485 / 100μlE45R29823N-AF488$485 / 100μlE45R29823N-AF514$485 / 100μlE45R29823N-AF532$485 / 100μlE45R29823N-AF555$485 / 100μlE45R29823N-AF568$485 / 100μlE45R29823N-AF405S$485 / 100μlE45R29823N-AF405L$485 / 100μlE45R29823N-AF546$485 / 100μlE45R29823N-AF594$485 / 100μlE45R29823N-AF610$485 / 100μlE45R29823N-AF635$485 / 100μlE45R29823N-AF647$485 / 100μlE45R29823N-AF680$485 / 100μlE45R29823N-AF700$485 / 100μlE45R29823N-AF750$485 / 100μlE45R29823N-AF790$485 / 100μlE45R29823N-APC$485 / 100μlE45R29823N-PE$485 / 100μlE45R29823N-Cy3$485 / 100μlE45R29823N-Cy5$485 / 100μlE45R29823N-Cy5.5$485 / 100μlE45R29823N-Cy7$485 / 100μlE45R29823N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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PTEN Rabbit pAb | EnoGene Biotech Co. Ltd