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ARIH1 Rabbit pAb
Human, Mouse, Rat
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5517783
TypePolyclonal Antibodies
HostRabbit
Positive control293T, Mouse testis, Rat testis
IsotypeIgG
SummaryE3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 UBE2L3. Acts as an atypical E3 ubiquitin-protein ligase by working together with cullin-RING ubiquitin ligase (CRL complexes and initiating ubiquitination of CRL substrates: associates with CRL complexes and specifically mediates addition of the first ubiquitin on CRLs targets. The initial ubiquitin is then elongated by CDC34/UBE2R1 and UBE2R2. E3 ubiquitin-protein ligase activity is activated upon binding to neddylated cullin-RING ubiquitin ligase complexes. Plays a role in protein translation in response to DNA damage by mediating ubiquitination of EIF4E2, the consequences of EIF4E2 ubiquitination are however unclear. According to a report, EIF4E2 ubiquitination leads to promote EIF4E2 cap-binding and protein translation arrest. According to another report EIF4E2 ubiquitination leads to its subsequent degradation. Acts as the ligase involved in ISGylation of EIF4E2. In vitro, controls the degradation of the LINC (LInker of Nucleoskeleton and Cytoskeleton complex member SUN2 and may therefore have a role in the formation and localization of the LINC complex, and as a consequence, nuclear subcellular localization and nuclear morphology.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human ARIH1 (NP_005735.2).
PurificationAffinity purification
Gene ID25820
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
All Names
AlternameARIH1; ARI; HARI; HHARI; UBCH7BP
Conjugated Antibody
This product is also available conjugated. Format: E45R29748N-Conjugate. Price: $485 / Size: 100μl.
E45R29748N-FITC$485 / 100μlE45R29748N-Biotin$485 / 100μlE45R29748N-HRP$485 / 100μlE45R29748N-AP$485 / 100μlE45R29748N-AF350$485 / 100μlE45R29748N-AF405M$485 / 100μlE45R29748N-AF488$485 / 100μlE45R29748N-AF514$485 / 100μlE45R29748N-AF532$485 / 100μlE45R29748N-AF555$485 / 100μlE45R29748N-AF568$485 / 100μlE45R29748N-AF405S$485 / 100μlE45R29748N-AF405L$485 / 100μlE45R29748N-AF546$485 / 100μlE45R29748N-AF594$485 / 100μlE45R29748N-AF610$485 / 100μlE45R29748N-AF635$485 / 100μlE45R29748N-AF647$485 / 100μlE45R29748N-AF680$485 / 100μlE45R29748N-AF700$485 / 100μlE45R29748N-AF750$485 / 100μlE45R29748N-AF790$485 / 100μlE45R29748N-APC$485 / 100μlE45R29748N-PE$485 / 100μlE45R29748N-Cy3$485 / 100μlE45R29748N-Cy5$485 / 100μlE45R29748N-Cy5.5$485 / 100μlE45R29748N-Cy7$485 / 100μlE45R29748N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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