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BRSK2 Rabbit pAb
Human, Mouse
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5517751
TypePolyclonal Antibodies
HostRabbit
Positive controlU-87MG, A-549, Mouse brain
IsotypeIgG
SummarySerine/threonine-protein kinase that plays a key role in polarization of neurons and axonogenesis, cell cycle progress and insulin secretion. Phosphorylates CDK16, CDC25C, MAPT/TAU, PAK1 and WEE1. Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU at 'Thr-529' and 'Ser-579'. Also regulates neuron polarization by mediating phosphorylation of WEE1 at 'Ser-642' in postmitotic neurons, leading to down-regulate WEE1 activity in polarized neurons. Plays a role in the regulation of the mitotic cell cycle progress and the onset of mitosis. Plays a role in the regulation of insulin secretion in response to elevated glucose levels, probably via phosphorylation of CDK16 and PAK1. While BRSK2 phosphorylated at Thr-174 can inhibit insulin secretion, BRSK2 phosphorylated at Thr-260 can promote insulin secretion. Regulates reorganization of the actin cytoskeleton. May play a role in the apoptotic response triggered by endoplasmic reticulum (ER stress.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenA synthetic peptide of human BRSK2.
PurificationAffinity purification
Gene ID9024
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
All Names
AlternameBRSK2; C11orf7; PEN11B; SAD1; SADA; STK29
Conjugated Antibody
This product is also available conjugated. Format: E45R29716N-Conjugate. Price: $485 / Size: 100μl.
E45R29716N-FITC$485 / 100μlE45R29716N-Biotin$485 / 100μlE45R29716N-HRP$485 / 100μlE45R29716N-AP$485 / 100μlE45R29716N-AF350$485 / 100μlE45R29716N-AF405M$485 / 100μlE45R29716N-AF488$485 / 100μlE45R29716N-AF514$485 / 100μlE45R29716N-AF532$485 / 100μlE45R29716N-AF555$485 / 100μlE45R29716N-AF568$485 / 100μlE45R29716N-AF405S$485 / 100μlE45R29716N-AF405L$485 / 100μlE45R29716N-AF546$485 / 100μlE45R29716N-AF594$485 / 100μlE45R29716N-AF610$485 / 100μlE45R29716N-AF635$485 / 100μlE45R29716N-AF647$485 / 100μlE45R29716N-AF680$485 / 100μlE45R29716N-AF700$485 / 100μlE45R29716N-AF750$485 / 100μlE45R29716N-AF790$485 / 100μlE45R29716N-APC$485 / 100μlE45R29716N-PE$485 / 100μlE45R29716N-Cy3$485 / 100μlE45R29716N-Cy5$485 / 100μlE45R29716N-Cy5.5$485 / 100μlE45R29716N-Cy7$485 / 100μlE45R29716N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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