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BAZ2A / TIP5 Rabbit pAb
Human, Mouse
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5517694
TypePolyclonal Antibodies
HostRabbit
Positive controlK-562, HeLa, NIH/3T3
IsotypeIgG
SummaryRegulatory subunit of the ATP-dependent NoRC-1 and NoRC-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. Both complexes regulate the spacing of nucleosomes along the chromatin and have the ability to slide mononucleosomes to the center of a DNA template. Directly stimulates the ATPase activity of SMARCA5 in the NoRC-5 ISWI chromatin remodeling complex. The NoRC-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the NoRC-5 ISWI chromatin remodeling complex. Within the NoRC-5 ISWI chromatin remodeling complex, mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing (By similarity. In the complex, it plays a central role by being recruited to rDNA and by targeting chromatin modifying enzymes such as HDAC1, leading to repress RNA polymerase I transcription (By similarity. Recruited to rDNA via its interaction with TTF1 and its ability to recognize and bind histone H4 acetylated on 'Lys-16' (H4K16ac, leading to deacetylation of H4K5ac, H4K8ac, H4K12ac but not H4K16ac (By similarity. Specifically binds pRNAs, 150-250 nucleotide RNAs that are complementary in sequence to the rDNA promoter; pRNA-binding is required for heterochromatin formation and rDNA silencing (By similarity.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein of Human BAZ2A（TIP5）.
PurificationAffinity purification
Gene ID11176
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
All Names
AlternameTIP5; WALp3; BAZ2A / TIP5; BAZ2A
Conjugated Antibody
This product is also available conjugated. Format: E45R29659N-Conjugate. Price: $485 / Size: 100μl.
E45R29659N-FITC$485 / 100μlE45R29659N-Biotin$485 / 100μlE45R29659N-HRP$485 / 100μlE45R29659N-AP$485 / 100μlE45R29659N-AF350$485 / 100μlE45R29659N-AF405M$485 / 100μlE45R29659N-AF488$485 / 100μlE45R29659N-AF514$485 / 100μlE45R29659N-AF532$485 / 100μlE45R29659N-AF555$485 / 100μlE45R29659N-AF568$485 / 100μlE45R29659N-AF405S$485 / 100μlE45R29659N-AF405L$485 / 100μlE45R29659N-AF546$485 / 100μlE45R29659N-AF594$485 / 100μlE45R29659N-AF610$485 / 100μlE45R29659N-AF635$485 / 100μlE45R29659N-AF647$485 / 100μlE45R29659N-AF680$485 / 100μlE45R29659N-AF700$485 / 100μlE45R29659N-AF750$485 / 100μlE45R29659N-AF790$485 / 100μlE45R29659N-APC$485 / 100μlE45R29659N-PE$485 / 100μlE45R29659N-Cy3$485 / 100μlE45R29659N-Cy5$485 / 100μlE45R29659N-Cy5.5$485 / 100μlE45R29659N-Cy7$485 / 100μlE45R29659N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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