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[KO Validated] PRKAR1A Rabbit pAb

E45R29623NDatasheetCOAMSDS
Human
P10644
$477/ 100 µl
Quantity
Total: $477

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5517658
TypePolyclonal Antibodies
HostRabbit
Positive control293T
IsotypeIgG
SummarycAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. This gene encodes one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids. Mutations in this gene cause Carney complex (CNC). This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2. A nonconventional nuclear localization sequence (NLS) has been found for this protein which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40). Several alternatively spliced transcript variants encoding two different isoforms have been observed.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price477$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human PRKAR1A (NP_002725.1).
PurificationAffinity purification
Gene ID5573
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200

All Names

AlternamePRKAR1A; ACRDYS1; ADOHR; CAR; CNC; CNC1; PKR1; PPNAD1; PRKAR1; TSE1
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R29623N-Conjugate. Price: $485 / Size: 100μl.

E45R29623N-FITC$485 / 100μlE45R29623N-Biotin$485 / 100μlE45R29623N-HRP$485 / 100μlE45R29623N-AP$485 / 100μlE45R29623N-AF350$485 / 100μlE45R29623N-AF405M$485 / 100μlE45R29623N-AF488$485 / 100μlE45R29623N-AF514$485 / 100μlE45R29623N-AF532$485 / 100μlE45R29623N-AF555$485 / 100μlE45R29623N-AF568$485 / 100μlE45R29623N-AF405S$485 / 100μlE45R29623N-AF405L$485 / 100μlE45R29623N-AF546$485 / 100μlE45R29623N-AF594$485 / 100μlE45R29623N-AF610$485 / 100μlE45R29623N-AF635$485 / 100μlE45R29623N-AF647$485 / 100μlE45R29623N-AF680$485 / 100μlE45R29623N-AF700$485 / 100μlE45R29623N-AF750$485 / 100μlE45R29623N-AF790$485 / 100μlE45R29623N-APC$485 / 100μlE45R29623N-PE$485 / 100μlE45R29623N-Cy3$485 / 100μlE45R29623N-Cy5$485 / 100μlE45R29623N-Cy5.5$485 / 100μlE45R29623N-Cy7$485 / 100μlE45R29623N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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[KO Validated] PRKAR1A Rabbit pAb | EnoGene Biotech Co. Ltd