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[KO Validated] GCN1L1 Rabbit pAb

E45R29522NDatasheetCOAMSDS
Human
Q92616
$477/ 100 µl
Quantity
Total: $477

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5517557
TypePolyclonal Antibodies
HostRabbit
Positive control293T
IsotypeIgG
SummaryActs as a positive activator of the EIF2AK4/GCN2 protein kinase activity in response to amino acid starvation. Forms a complex with EIF2AK4/GCN2 on translating ribosomes; during this process, GCN1 seems to act as a chaperone to facilitate delivery of uncharged tRNAs that enter the A site of ribosomes to the tRNA-binding domain of EIF2AK4/GCN2, and hence stimulating EIF2AK4/GCN2 kinase activity. Participates in the repression of global protein synthesis and in gene-specific mRNA translation activation, such as the transcriptional activator ATF4, by promoting the EIF2AK4/GCN2-mediated phosphorylation of eukaryotic translation initiation factor 2 (eIF-2-alpha/EIF2S1 on 'Ser-52', and hence allowing ATF4-mediated reprogramming of amino acid biosynthetic gene expression to alleviate nutrient depletion.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price477$
ImmunogenRecombinant protein of human GCN1L1.
PurificationAffinity purification
Gene ID10985
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200

All Names

AlternameGCN1; GCN1L; GCN1L1; PRIC295
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R29522N-Conjugate. Price: $485 / Size: 100μl.

E45R29522N-FITC$485 / 100μlE45R29522N-Biotin$485 / 100μlE45R29522N-HRP$485 / 100μlE45R29522N-AP$485 / 100μlE45R29522N-AF350$485 / 100μlE45R29522N-AF405M$485 / 100μlE45R29522N-AF488$485 / 100μlE45R29522N-AF514$485 / 100μlE45R29522N-AF532$485 / 100μlE45R29522N-AF555$485 / 100μlE45R29522N-AF568$485 / 100μlE45R29522N-AF405S$485 / 100μlE45R29522N-AF405L$485 / 100μlE45R29522N-AF546$485 / 100μlE45R29522N-AF594$485 / 100μlE45R29522N-AF610$485 / 100μlE45R29522N-AF635$485 / 100μlE45R29522N-AF647$485 / 100μlE45R29522N-AF680$485 / 100μlE45R29522N-AF700$485 / 100μlE45R29522N-AF750$485 / 100μlE45R29522N-AF790$485 / 100μlE45R29522N-APC$485 / 100μlE45R29522N-PE$485 / 100μlE45R29522N-Cy3$485 / 100μlE45R29522N-Cy5$485 / 100μlE45R29522N-Cy5.5$485 / 100μlE45R29522N-Cy7$485 / 100μlE45R29522N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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[KO Validated] GCN1L1 Rabbit pAb | EnoGene Biotech Co. Ltd