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[KO Validated] STRAP Rabbit pAb

E45R29445NDatasheetCOAMSDS
Human, Mouse, Rat
Q9Y3F4
$477/ 100 µl
Quantity
Total: $477

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5517480
TypePolyclonal Antibodies
HostRabbit
Positive control293T
IsotypeIgG
SummaryThe SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs, the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate. Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP. STRAP plays a role in the cellular distribution of the SMN complex. Negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price477$
ImmunogenRecombinant protein of human STRAP.
PurificationAffinity purification
Gene ID11171
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:1000 - 1:2000

All Names

AlternameSTRAP; MAWD; PT-WD; UNRIP
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R29445N-Conjugate. Price: $485 / Size: 100μl.

E45R29445N-FITC$485 / 100μlE45R29445N-Biotin$485 / 100μlE45R29445N-HRP$485 / 100μlE45R29445N-AP$485 / 100μlE45R29445N-AF350$485 / 100μlE45R29445N-AF405M$485 / 100μlE45R29445N-AF488$485 / 100μlE45R29445N-AF514$485 / 100μlE45R29445N-AF532$485 / 100μlE45R29445N-AF555$485 / 100μlE45R29445N-AF568$485 / 100μlE45R29445N-AF405S$485 / 100μlE45R29445N-AF405L$485 / 100μlE45R29445N-AF546$485 / 100μlE45R29445N-AF594$485 / 100μlE45R29445N-AF610$485 / 100μlE45R29445N-AF635$485 / 100μlE45R29445N-AF647$485 / 100μlE45R29445N-AF680$485 / 100μlE45R29445N-AF700$485 / 100μlE45R29445N-AF750$485 / 100μlE45R29445N-AF790$485 / 100μlE45R29445N-APC$485 / 100μlE45R29445N-PE$485 / 100μlE45R29445N-Cy3$485 / 100μlE45R29445N-Cy5$485 / 100μlE45R29445N-Cy5.5$485 / 100μlE45R29445N-Cy7$485 / 100μlE45R29445N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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[KO Validated] STRAP Rabbit pAb | EnoGene Biotech Co. Ltd