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[KO Validated] LAMTOR1 Rabbit pAb
Human, Mouse, Rat
$477/ 100 µl
QuantityTotal: $477
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5517479
TypePolyclonal Antibodies
HostRabbit
Positive controlHeLa
IsotypeIgG
SummaryAs part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulator complex to membranes. Also required for late endosomes/lysosomes biogenesis it may regulate both the recycling of receptors through endosomes and the MAPK signaling pathway through recruitment of some of its components to late endosomes. May be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes/lysosomes. May also play a role in RHOA activation.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price477$
ImmunogenRecombinant protein of human LAMTOR1.
PurificationAffinity purification
Gene ID55004
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:1000
IHC 1:50 - 1:100
IF 1:50 - 1:100
IHC 1:50 - 1:100
IF 1:50 - 1:100
All Names
AlternameLAMTOR1; C11orf59; PDRO; Ragulator1; p18; p27RF-Rho
Conjugated Antibody
This product is also available conjugated. Format: E45R29444N-Conjugate. Price: $485 / Size: 100μl.
E45R29444N-FITC$485 / 100μlE45R29444N-Biotin$485 / 100μlE45R29444N-HRP$485 / 100μlE45R29444N-AP$485 / 100μlE45R29444N-AF350$485 / 100μlE45R29444N-AF405M$485 / 100μlE45R29444N-AF488$485 / 100μlE45R29444N-AF514$485 / 100μlE45R29444N-AF532$485 / 100μlE45R29444N-AF555$485 / 100μlE45R29444N-AF568$485 / 100μlE45R29444N-AF405S$485 / 100μlE45R29444N-AF405L$485 / 100μlE45R29444N-AF546$485 / 100μlE45R29444N-AF594$485 / 100μlE45R29444N-AF610$485 / 100μlE45R29444N-AF635$485 / 100μlE45R29444N-AF647$485 / 100μlE45R29444N-AF680$485 / 100μlE45R29444N-AF700$485 / 100μlE45R29444N-AF750$485 / 100μlE45R29444N-AF790$485 / 100μlE45R29444N-APC$485 / 100μlE45R29444N-PE$485 / 100μlE45R29444N-Cy3$485 / 100μlE45R29444N-Cy5$485 / 100μlE45R29444N-Cy5.5$485 / 100μlE45R29444N-Cy7$485 / 100μlE45R29444N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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