Product Information
Cite ID#EN5517347
TypePolyclonal Antibodies
HostRabbit
Positive controlRat lung
IsotypeIgG
SummarySubstrate-specific adapter of a BCR (BTB-CUL3-RBX1 E3 ubiquitin ligase complex that acts as a regulator of neural crest specification. The BCR(KBTBD8 complex acts by mediating monoubiquitination of NOLC1 and TCOF1: monoubiquitination promotes the formation of a NOLC1-TCOF1 complex that acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
ImmunogenRecombinant protein of human KBTBD8.
PurificationAffinity purification
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IF 1:50 - 1:200
All Names
AlternameTA-KRP; TAKRP; KBTBD8