Product Information
Cite ID#EN5517305
TypePolyclonal Antibodies
HostRabbit
Positive controlA375, A-431, HepG2, TE-1, SGC-7901, Mouse stomach, Mouse liver, Rat stomach, Rat liver
IsotypeIgG
SummaryThe protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.