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Pan Cadherin Rabbit pAb
Human, Mouse, Rat
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5517289
TypePolyclonal Antibodies
HostRabbit
Positive controlPC-3, A-431, Mouse brain, Rat brain
IsotypeIgG
SummaryCadherin is one of a class of integral-membrane glycoproteins that are involved in cell to cell attachment for preserving the integrity of all solid tissues. Cadherins have three major regions: the Ca2+ -dependent extracellular region that mediates adhesion (cadherin to cadherin) for cell to cell binding; the transmembrane region; and the cytoplasmic region that extends into the cell and interacts with catenins, which in turn are linked to the actin of the cytoskeleton. Cadherins are differentially expressed during development and in adult organs. Since many cell types express multiple cadherin subclasses simultaneously (the combination differs with cell type), it can be inferred that the adhesion properities of individual cells are thus governed by varying the combinations of cadherins. Altered expression of cadherins are involved in invasion and metastasis of tumour cells. The classical cadherins (e.g. E-, N-, and P-cadherins) are the most common family members. E-cadherin (also known as uvomorulin) is concentrated in the belt desmosome in epithelial cells; N-cadherin is found in nerve, muscle, and lens cells and helps maintain the integrity of neuronal aggregates; P-cadherin is expressed in placental and epidermal cells.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 800-882 of pan-cadherin (NP_004351.1).
PurificationAffinity purification
Gene ID999/1000/1001/1002
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IP 1:50 - 1:200
IP 1:50 - 1:200
Conjugated Antibody
This product is also available conjugated. Format: E45R29253N-Conjugate. Price: $485 / Size: 100μl.
E45R29253N-FITC$485 / 100μlE45R29253N-Biotin$485 / 100μlE45R29253N-HRP$485 / 100μlE45R29253N-AP$485 / 100μlE45R29253N-AF350$485 / 100μlE45R29253N-AF405M$485 / 100μlE45R29253N-AF488$485 / 100μlE45R29253N-AF514$485 / 100μlE45R29253N-AF532$485 / 100μlE45R29253N-AF555$485 / 100μlE45R29253N-AF568$485 / 100μlE45R29253N-AF405S$485 / 100μlE45R29253N-AF405L$485 / 100μlE45R29253N-AF546$485 / 100μlE45R29253N-AF594$485 / 100μlE45R29253N-AF610$485 / 100μlE45R29253N-AF635$485 / 100μlE45R29253N-AF647$485 / 100μlE45R29253N-AF680$485 / 100μlE45R29253N-AF700$485 / 100μlE45R29253N-AF750$485 / 100μlE45R29253N-AF790$485 / 100μlE45R29253N-APC$485 / 100μlE45R29253N-PE$485 / 100μlE45R29253N-Cy3$485 / 100μlE45R29253N-Cy5$485 / 100μlE45R29253N-Cy5.5$485 / 100μlE45R29253N-Cy7$485 / 100μlE45R29253N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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