Product Information
Cite ID#EN5517276
TypePolyclonal Antibodies
HostRabbit
Positive controlMouse testis, Mouse brain, Mouse spleen, Rat testis, Rat thymus
IsotypeIgG
SummaryCentromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.