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Phospho-RIPK1/RIP-S166 Rabbit pAb

Human, Mouse
Q8NFZ0
$510/ 100 µl
Quantity
Total: $510

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5517110
TypePhosphorylated Antibodies
HostRabbit
Positive controlHT-29, NIH/3T3
IsotypeIgG
Summary3'-5' DNA helicase and substrate-recognition component of the SCF(FBH1 E3 ubiquitin ligase complex that plays a key role in response to stalled/damaged replication forks. Involved in genome maintenance by acting as an anti-recombinogenic helicase and preventing extensive strand exchange during homologous recombination: promotes RAD51 filament dissolution from stalled forks, thereby inhibiting homologous recombination and preventing excessive recombination. Also promotes cell death and DNA double-strand breakage in response to replication stress: together with MUS81, promotes the endonucleolytic DNA cleavage following prolonged replication stress via its helicase activity, possibly to eliminate cells with excessive replication stress. Plays a major role in remodeling of stalled DNA forks by catalyzing fork regression, in which the fork reverses and the two nascent DNA strands anneal. In addition to the helicase activity, also acts as the substrate-recognition component of the SCF(FBH1 E3 ubiquitin ligase complex, a complex that mediates ubiquitination of RAD51, leading to regulate RAD51 subcellular location.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price510$
ImmunogenA phospho specific peptide corresponding to residues surrounding S166 of human RIPK1/RIP
PurificationAffinity purification
Gene ID8737
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000

All Names

AlternameRIP; RIP-1; RIP1; RIPK1

Conjugated Antibody

This product is also available conjugated. Format: E45R29074N-Conjugate. Price: $485 / Size: 100μl.

E45R29074N-FITC$485 / 100μlE45R29074N-Biotin$485 / 100μlE45R29074N-HRP$485 / 100μlE45R29074N-AP$485 / 100μlE45R29074N-AF350$485 / 100μlE45R29074N-AF405M$485 / 100μlE45R29074N-AF488$485 / 100μlE45R29074N-AF514$485 / 100μlE45R29074N-AF532$485 / 100μlE45R29074N-AF555$485 / 100μlE45R29074N-AF568$485 / 100μlE45R29074N-AF405S$485 / 100μlE45R29074N-AF405L$485 / 100μlE45R29074N-AF546$485 / 100μlE45R29074N-AF594$485 / 100μlE45R29074N-AF610$485 / 100μlE45R29074N-AF635$485 / 100μlE45R29074N-AF647$485 / 100μlE45R29074N-AF680$485 / 100μlE45R29074N-AF700$485 / 100μlE45R29074N-AF750$485 / 100μlE45R29074N-AF790$485 / 100μlE45R29074N-APC$485 / 100μlE45R29074N-PE$485 / 100μlE45R29074N-Cy3$485 / 100μlE45R29074N-Cy5$485 / 100μlE45R29074N-Cy5.5$485 / 100μlE45R29074N-Cy7$485 / 100μlE45R29074N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

Phospho-RIPK1/RIP-S166 Rabbit pAb | EnoGene Biotech Co. Ltd