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HAVCR2 Rabbit pAb

E45R29027NDatasheetCOAMSDS
Human, Mouse, Rat
Q8VIM0
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5517063
TypePolyclonal Antibodies
HostRabbit
Positive controlRaji, RAW264.7, Mouse thymus, Rat spleen, Rat thymus
IsotypeIgG
SummaryT cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), isa transmembrane glycoprotein of the TIM family of immune regulating molecules and plays an important rolein the Th1-mediated immune response. TIM3 is expressed on the Th1 cells, CD8 T-cells, monocytes, anddendritic cells, but not on Th2 cells. TIM3 expressed by monocytes and dendritic cells facilitates phagocytosisof apoptotic cells and up-regulates cross-presentation of apoptotic cell-associated antigens through interactionwith phosphatidylserine. Engagement of TIM3 by its ligand galectin-9 induces a range of immunosuppressivefunctions which enhance immune tolerance and inhibit anti-tumor immunity. Stimulation of TIM3 with anagonistic antibody promotes inflammation through the activation of innate immune cells. TIM3 is alsoregarded as a potential target molecule for immunotherapy. TIM3 and programmed cell death 1 (PD-1) as twoimportant coinhibitory regulators of T cell responses, have been implicated with the T-cell dysfunction orexhaustion associated with chronic HBV infection including HBV-related HCC.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant protein of Mouse HAVCR2.
PurificationAffinity purification
Gene ID171285
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000

All Names

AlternameTim; TIM-; Tim3; Timd; TIM-3; Timd3
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R29027N-Conjugate. Price: $485 / Size: 100μl.

E45R29027N-FITC$485 / 100μlE45R29027N-Biotin$485 / 100μlE45R29027N-HRP$485 / 100μlE45R29027N-AP$485 / 100μlE45R29027N-AF350$485 / 100μlE45R29027N-AF405M$485 / 100μlE45R29027N-AF488$485 / 100μlE45R29027N-AF514$485 / 100μlE45R29027N-AF532$485 / 100μlE45R29027N-AF555$485 / 100μlE45R29027N-AF568$485 / 100μlE45R29027N-AF405S$485 / 100μlE45R29027N-AF405L$485 / 100μlE45R29027N-AF546$485 / 100μlE45R29027N-AF594$485 / 100μlE45R29027N-AF610$485 / 100μlE45R29027N-AF635$485 / 100μlE45R29027N-AF647$485 / 100μlE45R29027N-AF680$485 / 100μlE45R29027N-AF700$485 / 100μlE45R29027N-AF750$485 / 100μlE45R29027N-AF790$485 / 100μlE45R29027N-APC$485 / 100μlE45R29027N-PE$485 / 100μlE45R29027N-Cy3$485 / 100μlE45R29027N-Cy5$485 / 100μlE45R29027N-Cy5.5$485 / 100μlE45R29027N-Cy7$485 / 100μlE45R29027N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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HAVCR2 Rabbit pAb | EnoGene Biotech Co. Ltd