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SARM1 Rabbit pAb

E45R28994NDatasheetCOAMSDS
Human
Q6SZW1
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5517030
TypePolyclonal Antibodies
HostRabbit
Positive control293T, SH-SY5Y
IsotypeIgG
SummaryNAD(+ hydrolase, which plays a key role in axonal degeneration following injury by regulating NAD(+ metabolism. Acts as a negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway by promoting Wallerian degeneration, an injury-induced form of programmed subcellular death which involves degeneration of an axon distal to the injury site. Wallerian degeneration is triggered by NAD(+ depletion: in response to injury, SARM1 is activated and catalyzes cleavage of NAD(+ into ADP-D-ribose (ADPR, cyclic ADPR (cADPR and nicotinamide; NAD(+ cleavage promoting cytoskeletal degradation and axon destruction. Also able to hydrolyze NADP(+, but not other NAD(+-related molecules. Can activate neuronal cell death in response to stress. Regulates dendritic arborization through the MAPK4-JNK pathway (By similarity. Involved in innate immune response: inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant protein of human SARM1.
PurificationAffinity purification
Gene ID23098
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IP 1:50 - 1:200

All Names

AlternameSARM; HsTIR; SAMD2; hSARM1; MyD88-5
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R28994N-Conjugate. Price: $485 / Size: 100μl.

E45R28994N-FITC$485 / 100μlE45R28994N-Biotin$485 / 100μlE45R28994N-HRP$485 / 100μlE45R28994N-AP$485 / 100μlE45R28994N-AF350$485 / 100μlE45R28994N-AF405M$485 / 100μlE45R28994N-AF488$485 / 100μlE45R28994N-AF514$485 / 100μlE45R28994N-AF532$485 / 100μlE45R28994N-AF555$485 / 100μlE45R28994N-AF568$485 / 100μlE45R28994N-AF405S$485 / 100μlE45R28994N-AF405L$485 / 100μlE45R28994N-AF546$485 / 100μlE45R28994N-AF594$485 / 100μlE45R28994N-AF610$485 / 100μlE45R28994N-AF635$485 / 100μlE45R28994N-AF647$485 / 100μlE45R28994N-AF680$485 / 100μlE45R28994N-AF700$485 / 100μlE45R28994N-AF750$485 / 100μlE45R28994N-AF790$485 / 100μlE45R28994N-APC$485 / 100μlE45R28994N-PE$485 / 100μlE45R28994N-Cy3$485 / 100μlE45R28994N-Cy5$485 / 100μlE45R28994N-Cy5.5$485 / 100μlE45R28994N-Cy7$485 / 100μlE45R28994N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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SARM1 Rabbit pAb | EnoGene Biotech Co. Ltd