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TAZ Rabbit pAb

Human, Mouse, Rat
IHC (Homo sapiens, Mus musculus)
ChIP (Mus musculus)
IF (Homo sapiens)
Q9GZV5
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5505380
TypePolyclonal Antibodies
HostRabbit
Positive controlMouse lung, Rat lung
IsotypeIgG
SummaryTranscriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation. In conjunction with YAP1, involved in the regulation of TGFB1-dependent SMAD2 and SMAD3 nuclear accumulation. Plays a key role in coupling SMADs to the transcriptional machinery such as the mediator complex. Regulates embryonic stem-cell self-renewal, promotes cell proliferation and epithelial-mesenchymal transition.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human TAZ (NP_056287.1).
PurificationAffinity purification
Gene ID25937
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

All Names

AlternameWW domain-containing transcription regulator protein 1; Transcriptional coactivator with PDZ-binding motif; TAZ; WWTR1

Conjugated Antibody

This product is also available conjugated. Format: E45R28035N-Conjugate. Price: $485 / Size: 100μl.

E45R28035N-FITC$485 / 100μlE45R28035N-Biotin$485 / 100μlE45R28035N-HRP$485 / 100μlE45R28035N-AP$485 / 100μlE45R28035N-AF350$485 / 100μlE45R28035N-AF405M$485 / 100μlE45R28035N-AF488$485 / 100μlE45R28035N-AF514$485 / 100μlE45R28035N-AF532$485 / 100μlE45R28035N-AF555$485 / 100μlE45R28035N-AF568$485 / 100μlE45R28035N-AF405S$485 / 100μlE45R28035N-AF405L$485 / 100μlE45R28035N-AF546$485 / 100μlE45R28035N-AF594$485 / 100μlE45R28035N-AF610$485 / 100μlE45R28035N-AF635$485 / 100μlE45R28035N-AF647$485 / 100μlE45R28035N-AF680$485 / 100μlE45R28035N-AF700$485 / 100μlE45R28035N-AF750$485 / 100μlE45R28035N-AF790$485 / 100μlE45R28035N-APC$485 / 100μlE45R28035N-PE$485 / 100μlE45R28035N-Cy3$485 / 100μlE45R28035N-Cy5$485 / 100μlE45R28035N-Cy5.5$485 / 100μlE45R28035N-Cy7$485 / 100μlE45R28035N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

TAZ Rabbit pAb | EnoGene Biotech Co. Ltd